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WHO Technical Consultation Report on IPTp

To prevent malaria during pregnancy, the World Health Organization recommends that all pregnant women in areas of stable transmission of Plasmodium falciparum receive at least two doses of intermittent preventive treatment (IPTp) after quickening, during regularly scheduled antenatal care visits. The most effective and efficacious drug to date is sulfadoxine-pyrimethamine (SP). Since this strategy was recommended in 1998, several African countries have adopted IPTp with SP as national policy.

More recently, there is evidence of increasing resistance of Plasmodium falciparum to SP. This and other changes to the context in which IPTp is being deployed, led WHO to convene a technical expert group from 11-13 July 2007 to appraise available evidence on IPTp. The recommendations and conclusions of the panel are included here in the report Technical Expert Group meeting on intermittent preventive treatment (IPTp). (WHO 2008)