Unitaid is funding a consortium, led by Expertise France, that seeks to eliminate cervical cancer in Burkina Faso, Côte d’Ivoire, Guatemala and the Philippines through secondary prevention (i.e., detecting disease early to slow or halt its progress). The three-year SUCCESS project is designed to shift the countries from a largely opportunistic cervical cancer screening model to a systematic approach centered on innovations related to: 1) reinforced and simplified cervical cancer screening through the introduction of human papilloma virus (HPV) testing with self-collection sampling; 2) secondary prevention of cervical cancer including use of efficient methods for treatment of cervical precancerous lesions such as thermal ablation; and 3) intensified dissemination of information on cervical cancer and new preventive technologies. In so doing, SUCCESS aims to support countries to “leapfrog” to a state-of-the-art services model recommended by the World Health Organization. As the implementing partner of the consortium, Jhpiego is integrating and expanding cervical cancer prevention and treatment services into both new and existing platforms, relying on our established relationships with governments and stakeholders in all four countries. Through demand-generation and community engagement activities, the project plans to screen a total of 185,000 women, a significant proportion of whom will be women living with HIV.